This study examines the impact of innovation, infrastructure, and industrialization on sustainable economic growth and tested about the moderating role of infrastructure on the relationship between innovation and sustainable economic growth. This research had implemented quantitative research design and primary data was collected from 235 respondents in Greater Hyderabad with web survey. Data analysis has implemented statistical tools such as multiple regression, moderation analysis, and descriptive statistics to analyze the relationships between variables in the research model. The findings of this research work had revealed that innovation, infrastructure and industrialization had strong positive effects on sustainable economic growth while innovation showing the greatest impact. The study had found that infrastructure significantly moderates the relationship between innovation and sustainable economic growth amplifying its positive effects. The research demonstrates the importance of promoting innovation and investing in infrastructure to achieve long-term sustainable development. Such insights present valuable implications for policymakers and business leaders for promoting sustainable economic systems and proposed avenues for future research on additional factors influencing economic sustainability.