One of the primary focuses of this inquiry on the effects of intravenous hypertonic saline administered prior to surgical procedures was hypotension that occurred following the induction of general anesthesia. The normal saline solution (13 ml/kg) or the hypertonic saline 5% solution (2.3 ml/kg) was administered to fifty patients who were scheduled to undergo elective surgery. Every group was given a number that was chosen at random. The administration of a hypertonic saline infusion that lasted for thirty minutes was carried out thirty minutes before the beginning of the anesthesia. During the process of giving anesthesia to each individual patient, a standard procedure was followed. A patient's age, gender, body mass index (BMI), blood pressure (both systolic and diastolic), heart rate (HR), and mean arterial pressure (MAP) were all assessed. A mean age of 36.68 years, with a standard deviation of 10.8 years, was documented for the patients. Forty percent of the patients were male for the group. In terms of the mean systolic blood pressure (SBP) at minutes 2 and 5, the mean diastolic blood pressure (DBP) at minutes 2, 5, and 15, the mean heart rate (HR) at all time periods, and the mean maximum arterial pressure (MAP) at minutes 2 and 15, there was no significant difference between the groups. There was a significant difference between the normal group and the hypertonic saline group in terms of the mean systolic blood pressure (SBP) at minutes 10 and 15, the mean diastolic blood pressure (DBP) at minute 10, and the mean mean arterial pressure (MAP) at minutes 5 and 10, with the hypertonic saline group achieving a significantly higher value relative to the normal group (P < 0.05). It was determined that there was no statistically significant difference between the groups in terms of the trends of SBP, DBP, HR, and MAP (P > 0.05). The administration of a 5% hypertonic saline infusion (2.3 mg/kg) before to general anesthesia resulted in a positive reduction in both the mean arterial pressure (MAP) and the heart rate. Furthermore, there were no instances of severe hypotension that occurred.