Nanoparticle-based probes are emerging as alternatives to molecular probes due to their various advantages, such as bright and tunable optical property, enhanced chemical and photochemical stability, and ease of introduction of multifunctionality. In this article synthesis of nanoparticle of 1 2 4 -dithiadiazolidine derivative by using Tetra-O-acetyl-B-D-glucosyl thiocarbamide fusion with N-tetra-O-acetyl-β-D-galactosyl-S-chloroisothiocarbamoyl chloride These compounds arouse interest as potential biologically active substances and versatile intermediates for preparing various derivatives The identities of newly synthesis compounds have been established on the basis of usual chemical transformation and U.V, SEM, TEM Analytical studies.

Keywords: 1 2 4 -Dithiadiazolidine, N-tetra-O-acetyl-β-D-galactosyl-S-chloroisothiocarbamoyl Chloride, Glucosyl Thiocarbamides.