Indian drug and pharmaceutical companies are major producers of medical and pharmaceutical solutions in drugs and vaccines worldwide. In the Covid-19 pandemic, they have served a significant and remarkable way for human life-saving treatments. However, in the present study, a regression analysis has been carried out for the three noted pharmaceutical Indian multinational companies: Biocon, Cadila Pharmaceuticals and Cipla Ltd. The study is based on secondary data and data collected for a period of 10 years from 2011-12 to 2020-2021.The return on equity is taken as the independent variable whereas years taken as dependent variable. The purpose of this study is to find out the trend of relation between return on equity and years of study period. The findings indicate a strong relationship between these variables. The trend and regression analysis have found that the pharmaceutical companies’ return on equity had inversely proportional trend with time i.e.  the regression graphs showing downward trend with increasing time.

Keywords: Pharmaceutical Companies, Indian, Multinational, Return on Equity, Regression Analyses.