Fagonia bruguieri DC. is reported as a rare plant species from the Thar Desert. The plant is known for its adaptation to arid climatic conditions. A report on antioxidant phytochemicals in ethyl acetate fraction is not yet documented. In the present study, the presence of polar compounds in acetate fraction was identified by GC-MS assay. Antifungal activity was also conducted on five different fungal strains (Microsporum canis, Trichophyton rubrum, Epidermophyton floccosum, Penicillium chrysogeum, and Candida albicans). Resulting, GC-MS analysis of fraction identified a total of 16 compounds. Acetone crude extract is able to inhibit the growth of T. rubrum, C. albicans, and P. chrysogeum.

Keywords: Medicinal Plant, GC-MS, Antimicrobial Compound, Nonpolar Fraction, Antifungal.