In the light of sustainable and integrated ways of disease control, to minimize the uses of hazardous chemicals, the most of studies in the field of agricultural microbiology have been centered around been biological control. The biological control of wilt (Fusarium oxysporum) disease of Tomato, a soil-borne disease, through certain cellulolytic fungi notably Aspergillus spp. and Penicilliumspp. etc. has been envisioned in the present study. The invitro study of antagonistic effects of these cellulolytic fungi highlights the positive impact of compost prepared through the fungal cultures over the seed germination,  plant growth and vigour with reduced incidences of the disease compared to those treated with chemical fungicides. Such compost can be of significant commercial value in future.

Keywords: Hazardous Chemicals, Agricultural Microbiology, Chemical Fungicides, Soil-Borne Disease.